NutraBulk D-Ribose Powder ONE KILOGRAM Review

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(More customer reviews)I first learned of this supplement through Cardiologist Dr. Stephen Sinatra after reading his books and website for reversing heart disease. My husband is a type 2 diabetic with high blood pressure and has heart disease (syndrome X). Dr. Sinatra refers to the "Awesome Foursome" of supplements in which D-ribose is one of the four key supplements.
My husband reports "the performance of this product, in conjunction with the other supplements that comprise the 'awesome foursome', was instrumental in improving my health." He calculates that generally d-ribose lowered his blood glucose levels about 30 - 50 points, on average. Using d-ribose in conjunction with a daily exercise program and a lifestyle change (he now completely avoids bleached white flour, white rice, high fructose corn syrup, artificial sweeteners and soda) he now routinely has glucose levels of 90 - 120 where before this lifestyle change and supplements he was routinely having readings of 250 - 300 - all while taking the same dosage of his diabetes medication.
More importantly, it gave him a much needed energy boost - before taking d-ribose he appeared as a "sick cardiac patient" with a washed out skin tone and mentions he felt lifeless of energy. Today, 2 months after beginning the Awesome Foursome supplements, his appearance is much healthier, he's full of energy, and he's motivated to continue with a lifestyle change now that he can see major results. In his case he's even regrowing hair on some areas of his scalp where he has been bald for many years. We don't know what in particular is causing this new hair growth but he's not complaining! ;-)
What works for one person may not work for another so use due diligence when selecting any supplements and read as much as possible before using any of them. We found great information on d-Ribose in the National Institute of Health's archive of articles on Medline. [...] - see below.
The warning label on this container states "Cautions: diabetics should consult their medical provider before using D-Ribose and closely monitor blood glucose levels if taking supplemental D-Ribose."
Jeri
~~~~~~~~~~~
Abstracts of several articles we found on Medline:
Eur J Heart Fail. 2003 Oct;5(5):615-9.
D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study.
Omran H, Illien S, MacCarter D, St Cyr J, Luderitz B.
Department of Medicine-Cardiology, University of Bonn, Sigmund-Freud-Street 25, D-53105, Bonn, Germany. omran@uni-bonn.de
Patients with chronic coronary heart disease often suffer from congestive heart failure (CHF) despite multiple drug therapies. D-Ribose has been shown in animal models to improve cardiac energy metabolism and function following ischaemia. This was a prospective, double blind, randomized, crossover design study, to assess the effect of oral D-ribose supplementation on cardiac hemodynamics and quality of life in 15 patients with chronic coronary artery disease and CHF. The study consisted of two treatment periods of 3 weeks, during which either oral D-ribose or placebo was administered followed by a 1-week wash out period, and then administration of the other supplement. Assessment of myocardial functional parameters by echocardiography, quality of life using the SF-36 questionnaire and functional capacity using cycle ergometer testing was performed. The administration of D-ribose resulted in an enhancement of atrial contribution to left ventricular filling (40+/-11 vs. 45+/-9%, P=0.02), a smaller left atrial dimension (54+/-20 vs. 47+/-18 ml, P=0.02) and a shortened E wave deceleration (235+/-64 vs. 196+/-42, P=0.002) by echocardiography. Further, D-ribose also demonstrated a significant improvement of the patient's quality of life (417+/-118 vs. 467+/-128, P< or =0.01). In comparison, placebo did not result in any significant echocardiographic changes or in quality of life. This feasibility study in patients with coronary artery disease in CHF revealed the beneficial effects of D-ribose by improving diastolic functional parameters and enhancing quality of life.J Cardiovasc Pharmacol Ther. 2000 Oct;5(4):249-58.
D-Ribose as a supplement for cardiac energy metabolism.
Pauly DF, Pepine CJ.
Division of Cardiovascular Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA.
Metabolic support for the heart has been an attractive concept since the pioneering work of Sodi-Pallares et al. four decades ago.* Recently, interest has increased in the use of over-the-counter supplements and naturally occurring nutriceuticals for enhancement of cardiac and skeletal muscle performance. These include amino acids such as creatine, L-carnitine, and L-arginine, as well as vitamins and cofactors such as alpha-tocopherol and coenzyme Q. Like these other molecules, D-ribose is a naturally occurring compound. It is the sugar moiety of ATP and has also received interest as a metabolic supplement for the heart. The general hypothesis is that under certain pathologic cardiac conditions, nucleotides (particularly ATP, ADP, and AMP) are degraded and lost from the heart. The heart's ability to resynthesize ATP is then limited by the supply of D-ribose, which is a necessary component of the adenine nucleotide structure. In support of this hypothesis, recent reports have used D-ribose to increase tolerance to myocardial ischemia. Its use in patients with stable coronary artery disease improves time to exercise-induced angina and electrocardiographic changes. In conjunction with thallium imaging or dobutamine stress echocardiography, D-ribose supplementation has been used to enhance detection of hibernating myocardium. In this article, we review the biochemical basis for using supplemental D-ribose as metabolic support for the heart and discuss the experimental evidence for its benefit.Int J Cardiol. 2008 Mar 28;125(1):49-56. Epub 2007 Apr 16.
D-ribose improves cardiac contractility and hemodynamics, and reduces expression of c-fos in the hippocampus during sustained slow ventricular tachycardia in rats.
Schneider HJ, Rossner S, Pfeiffer D, Hagendorff A.
Medizinische Klinik und Poliklinik II, Universitätsklinikum Regensburg, Franz-Joseph-Strauss Allee 11, 93053 Regensburg, Deutschland, Germany. hans-juergen.sch@gmx.de
BACKGROUND: Moderate hypotension during hemodynamically stable ventricular tachycardia (VT), leads to cerebral ischemia. Supplementation of d-ribose has been shown to improve cardiac metabolism. We hypothesized that cerebral ischemia during slow VT may lead to the expression of immediate early genes related to neurodegeneration. This expression may be prevented by d-ribose substitution. METHODS: Slow VT was induced over 20 min by external left ventricular pacing after infusion of physiologic saline or d-ribose (450 mg/kg) in 44 rats. Different coloured microspheres were used for tissue blood flow measurements. Histochemistry of c-fos in cerebral tissue sections was performed. RESULTS: With the onset of VT, the mean arterial pressure (MAP) significantly dropped in both groups. However, the MAP in the d-ribose group was significantly higher (p

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ONE Kilogram of pharmaceutical grade D-Ribose Powder $72.99 a-D-Ribofuranose (D-Ribose) is found in each cell of the body and is an essential component for production of energy. The body uses D-Ribose to make nucleic acids, glycogen and most importantly the production of adenosine triphosphate (ATP) ? the body?s energy source. Adequate levels of ATP are critical for optimal health and athletic performance. Illness, strenuous or infrequent exercise, advancing age and a wide variety of metabolic disorders can drain the body?s cells of ATP resulting general fatigue, sore muscles and lack of energy. While the body can produce D-ribose on its own, it lacks the ability to do this quickly and efficiently. Research has shown supplemental D-Ribose significantly increases ATP production in both slow and fast twitch muscles and contributes to greater power and athletic endurance. Numerous studies show supplemental D-ribose reduces recovery time needed for heart and muscle tissue to replace ATP lost during strenuous exercise. Dosage: As a dietary supplement, mix one serving (5 grams) with water or other beverage 2-3 times dailey or as directed by your healthcare provider. Expiration Date: JULY 2012 These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease

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Solaray - Dl-Phenylalanine, 60 capsules Review

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(More customer reviews)Please Consult with your doctor before taking this product...
Low norepinephrine and dopamine levels are often associated with depression, lethargy, trouble focusing, negativity, and mental fuzziness...Also, I often have my patients take natural amino acids such as tyrosine (1,000-1,500 milligrams a day) for energy, focus, and impulsivity control, and dl-phenylalanine (400 milligrams three times a day on an empty stomach) for moodiness and irritability. ~Daniel G. Amen, Change Your Brain, Change Your Life
If you are considering this supplement, please consult with your physician. There may be a good reason for you NOT to take this product. I find that it is helpful for occasional depression (mild forms) and can enhance your love life by promoting feelings of being "in love." It can also be helpful for "love withdrawals."
Why does this product help? D-Phenylalanine can convert to phenylethylamine and that can make you feel "in love." I have also noticed that this product enhances your sex life and can increase pleasure in interesting ways. I figure it is simply because your body has a building block of pleasure and uses it to its advantage.
Taking this product can also make you act a bit silly and heady in certain circumstances. I notice I laugh (feel a bit giddy) a lot more when taking two pills and jokes are especially funny in comedies. When taking one pill I feel comforted, happy and more satisfied with life in general. While I don't take this every day, I can say that if you take this and then go out to Italian food, you will probably end up having great sex. I have also noticed I respond less severely to negativity and take things less seriously. I tend to turn negative situations into jokes or just ignore what people are saying and go on to think about something more pleasant. That type of reaction. I get less emotionally involved in negative situations.
So, think about being "in love" and how perfect the world seems and how the colors of the world stand out more. This is what this product can do if it is safe for you to take Phenylalanine.
Essential Amino Acids and Mood:
Amino acids aid in the production of hormones, "neurotransmitters" and enzymes.
Phenylalanie is an essential amino acid (cannot be produced by the body and must be obtained through diet), which is a building block for pleasure neurotransmitters (chemical compounds used for communication between neurons/brain cells). The human brain is made up of a web of billions of cells called neurons.
Essential amino acids: histidine, isoleucine, leucine, lysine, methionine, "phenylalanine," threonine, tryptopahn, and valine.
Nonessential amino acids: alanine, arginine, asparagines, aspartic acid, cysteine, glutamic acid, glutamine, gylcine, proline, serine, taurine, and tyrosine.
Basically Phenylalanine is a precursor for neurotransmitter biosynthesis. It is one of the 20 essential amino acids the body cannot synthesize (manufacture). The protein in food is a combination of chemical units called amino acids. When your body lacks even one amino acid, it can have a negative effect on your health.
How does this relate to Dopamine?
Phenylalanine helps to produce neurotransmitters, dopamine, norepinephrine, and epinephrine.
The primary monoamine neurotransmitters are "dopamine," norepinephrine and serotonin. Dopamine is associated with emotional response. Dopamine is often called the pleasure chemical and is also released at the moment of sexual climax, therefore the triggering of the feeling of bliss.
When we are "in love" our brains are overproducing dopamine. Dopamine is said to be responsible for feelings associated with sexual pleasure, romantic love, verbal fluency and creativity. Which I guess might explain why when we talk to someone who seems to be making us very happy, we suddenly feel the need to write poems. We can also have surges in dopamine when we are eating, listening to music or even looking at objects of beauty. Our rewards centers then release dopamine.
Why Take both D & L-Phenylalanine?
D-Phenylalanine can convert into phenylethylamine (PEA), the "love chemical" released into the bloodstream when a person falls in love. PEA is also found in chocolate, although many tests show it is broken down before it reaches the brain. Phenylethylamine does cross the blood brain barrier and it is associated with sexual attraction, emotional infatuation and the excitement of love.
Phenylalanine can:
Promote Sexual Arousal (I'd have to agree although some say this is not proven)
Elevate Mood and helps to Aleviate Depression
Decrease Pain
Aid Memory
Decrease Appetite (people who are in love can find a decrease in appetite to be normal)
Alleviate some symptoms of PMS (I also use Dandelion Tea)
Help to overcome alcoholism and other drug addictions. You can also get addicted to people.
L-Phenylalanine is converted to L-tyrosine, then L-dopa, then into norepinephrine. It is effective in reducing the symptoms of PMS.
D-Phenylalanine can convert into phenylethylamine and is capable of giving relief from back pain, arthritis and chronic pain.
The combination product called DL-Phenylalanine can be used to combat pain, elevate mood and encourage mental alertness.
STRONG CAUTIONS:
L-Phenylalanine can promote high blood pressure in anyone predisposed to hypertension.
Phenylalanine can promote the cell division of existing malignant melanoma cells. Avoid this product if you have any form of cancer.
THIS PRODUCT SHOULD BE AVOIDED BY ANYONE WHO HAS PHENYLKETONURIA (PKU), HIGH BLOOD PRESSURE OR CANCER. DO NOT TAKE WITH MAO inhibitor antidepressant drugs. Not recommended for pregnant or lactating women.
Please consult with your physician before taking this supplement. This information is not intended to replace the attention or advice of a physician or other health care professional.
Recommended Doses: 500 mg a day and then with your doctor's advice, you can work up to 1,500 mg a day. I find that 500 mg is sufficient and I up the dose to 1,000 mg a day if I'm planning for romance.
More is not Better. In fact, high doses of certain amino acids may be toxic and can produce nausea, vomiting and other unpleasant side effects.
~The Rebecca Review

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DL-Phenylalanine 500mg50/50 (Equimolar) Blend of D-Phenylalanine & L-PhenylalanineSolaray Guarantees that NO ingredients other than those listed on this label have been added to this product

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